Sigma-Aldrich
Guanidine Hydrochloride Organic Base 99% Titration 10 kg
- Part Number:
- MIL-G4505-10KG
- Lead Time:
- 7-14 days
- Minimum Purchase:
- 1 unit
- Shipping:
- FREE SHIPPING on most orders over $50*
- Quantity:
- each
- Size:
- 10 kg
- Style:
- chemical
- DOT Rated:
- HazMat Transport Fee Required
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Description
Guanidine Hydrochloride Organic Base ≥99% Titration 10 Kg
Synonym: Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride
- CAS Number 50-01-1
- Linear Formula NH2C(=NH)NH2 · HCl
- Molecular Weight 95.53
- Beilstein/REAXYS Number 3591990
- EC Number 200-002-3
- MDL number MFCD00013026
- PubChem Substance ID 24895176
| assay | ≥99% (titration) |
| pH | (25 °C, 4.6 - 6 at 573 g/L) |
| mp | 180-185 °C (lit.) |
| solubility | H2O: 6 M |
| absorption | ≤0.10 at 260 nm in H2O at 6 M |
| SMILES string | Cl[H].NC(N)=N |
| InChI | 1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H |
| InChI key | PJJJBBJSCAKJQF-UHFFFAOYSA-N |
Application
Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
GHS07
Signal word Warning
Hazard statements H302 + H332-H315-H319
Precautionary statements P261-P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS MF4300000
Documents
Warnings
Note: These chemicals are for research & laboratory use only. Your order will not be processed if you do not work for, and ship to, a registered laboratory or research facility. Not for topical applications. An official Declaration of Use form may be required.
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WARNING: This product can expose you to chemicals which are known to the State of California to cause cancer and reproductive harm. Prop 65 Warning
Please note: This product is not returnable.